News

Jan 21, 2019

There has been a fall-out over reimbursement rates, between Walmart and its pharmacy benefit manager network, CVS Caremark. This is just indicative of the power struggle taking place in the industry as players buy companies and combine for greater might. The company added that a very small proportion of people use Walmart exclusively to fill their prescriptions and thus this will not have an impact CVS Health's financial results this year. 

Jan 20, 2019

In this study, they evaluated a blood test for HPV-linked oropharyngeal squamous cell carcinoma, which is a cancer of the back of the throat. The findings demonstrated the test could be an effective and less costly alternative for monitoring for cancer recurrence after radiation treatment.

Jan 20, 2019

Here Diego, et al. presented preliminary results from a clinical study of investigational cellular immunotherapy for Hodgkin lymphoma and non-Hodgkin lymphoma expressing the CD30 protein marker. Data from the phase Ib/II trial showed that the treatment was safe, and it generated “excellent” responses when used after a specific chemotherapy regimen, researchers reported.

Journal Abstracts

Jan 18, 2019

This is a retrospective analysis to evaluate with reflectance confocal microscopy (RCM)  atypical melanocytic lesions identified in dermoscopy, according to common RCM criteria for the differential diagnosis of BCC and to identify representative RCM parameters for superficial (sBCCs) and nonsuperficial (nsBCCs) BCCs. Results suggest RCM is able to diagnose BCCs mimicking melanoma at dermoscopy.

Jan 18, 2019

This is a retrospective study to see the etiology of pleural effusion in our tertiary care center over 1 year period. Tuberculosis is one of the common causes of exudative effusions along with parapneumonic effusions and malignancy. Pleural fluid ADA levels are highly sensitive with good specificity for the diagnosis of etiology of tubercular effusions.

 

Jan 13, 2019

Williams DM, et al. performed two-sample Mendelian randomization analyses to investigate if Alzheimer disease (AD) risk would be lower in individuals with lifelong, genetically predicted increases in concentrations of 4 circulating antioxidants that are modifiable by diet. No reduction in AD risk was suggested in relation to higher exposure to ascorbate, β-carotene, retinol, or urate. There was little evidence to imply that pleiotropy had biased results.

Recent Articles

Feb 21, 2019

Watch Dr. Kapil from the National Eye Institute explain the role of Retinal Pigment Epithelium in AMD patients. 

Jan 21, 2019

This is a case of a 71-year-old female smoker presented with stage IV EGFR-mutated lung adenocarcinoma. She was started on erlotinib at 150 mg/day. However, by 28 days, severe pruritus and acneiform skin rush due to erlotinib. After recovery, she was restarted on erlotinib at 100 mg/day. However, severe pruritus and skin rush developed again which was subsided by  aprepitant for two times.  So, there is need of flexible adjustment of the treatment schedule for aprepitant administration.

Jan 21, 2019

A 13-year-old-boy came c/o left-sided abdominal pain without fever, nausea, vomiting, or genitourinary symptoms. O/E his vitals were within normal limits. X-Ray Abdomen did not show any positive findings. A USG showed a mass 7 cm in diameter, located anteriorly and inferiorly to the spleen with similar structure. MRI confirmed these findings, and also showed intracapsular hemorrhage in the mass. Thus the diagnosis of a giant accessory spleen was made. This spleen was removed surgically and the child showed uneventful recovery. 

Case Studies

Jan 21, 2019

A 24-year-old healthy female patient reported with a chief complaint of poor esthetics in the upper front tooth region with retained deciduous teeth. On oral examination, there were retained deciduous teeth (52, 53, and 63) with congenitally missing permanent successors. The retained deciduous teeth were extracted, and immediate implant placement was done in the extraction sockets along with L-PRF membranes in one surgical session under local anesthesia. Immediate temporization was performed with composite crowns on immediately placed dental implants.

Jan 21, 2019

A 13-year-old-boy came c/o left-sided abdominal pain without fever, nausea, vomiting, or genitourinary symptoms. O/E his vitals were within normal limits. X-Ray Abdomen did not show any positive findings. A USG showed a mass 7 cm in diameter, located anteriorly and inferiorly to the spleen with similar structure. MRI confirmed these findings, and also showed intracapsular hemorrhage in the mass. Thus the diagnosis of a giant accessory spleen was made. This spleen was removed surgically and the child showed uneventful recovery. 

Jan 21, 2019

A 77-year-old-female, k/c/o hypertension, untreated hyperlipidemia, hypothyroidism was referred for treadmill stress test. She had no p/h/o any cardiac symptoms. O/E she had a systolic ejection murmur that was graded II/VI at the base. ECG showed normal findings with occasional PVCs. During the stress test, stage-one lasted for three minutes but was terminated due to dyspnoea w/o chest pain. Her dyspnoea worsened with tightness in her chest. Post emergency management she was transferred for cardiac-catheterisation. This was then diagnosed to be treadmill-induced mid-left ventricular ballooning variant of takotsubo cardiomyopathy. 

Jan 21, 2019

A 7-month-old-male baby presented post a generalized tonic-clonic seizure. He had normal birth-history and no h/o any illness post birth. Neurologic exam demonstrated brisk patellar reflexes, and was low on calcium and undetectable levels of Vitamin D, elevated parathyroid hormone and alkaline phosphatase levels. His X-Ray showed rachitic changes. The diagnosis of nutritional rickets was made. He was treated with Calcium and Vitamin D. Post that his urine output diminished and he became lethargic. Investigations were positive for Acute Renal Failure, metabolic acidosis, and hyperkalemia. He recovered with routine management and was discharged on day 4 on oral vitamin D and calcium supplementation.