News

Oct 21, 2019

Roche’s Tecentriq immunotherapy mixed with the older cancer drug Avastin lifted both overall survival and progression-free survival in people with liver cancer that cannot be surgically removed, the Swiss drugmaker said.

Oct 21, 2019

In a study using non-invasive tape strips in young children with eczema (or atopic dermatitis), researchers found many molecular signs of immune dysfunction and skin changes that relate to disease activity. These signs (or biomarkers) were present even before eczema was visible and can be used to track disease activity over time. This study was the most comprehensive to date to demonstrate that tape strips can be used in infants and young children instead of painful biopsies to assess early-onset atopic dermatitis on the molecular level

Oct 21, 2019

Stéphanie Lacour's team at EPFL's Laboratory for Soft BioElectronic Interface (LSBI) worked with clinicians from Harvard Medical School and Massachusetts Eye and Ear to develop a soft electronic interface. The highly elastic implant conforms neatly to the curved surface of the auditory brainstem and can, therefore, send highly targeted electrical signals. It has been tested successfully on mice - the implant has a surface area only 0.25 mm2 - and has now been produced at a size suitable for human use and in a form that is compatible with current surgical techniques.

Journal Abstracts

Oct 21, 2019

This cross-sectional study has assessed the knowledge, attitudes, and practices of cervical cancer and screening amongst female healthcare professionals at King Fahad Medical City (KFMC), Saudi Arabia. The study population showed poor knowledge of cervical cancer as a disease. The participants had a fair knowledge of Pap smear testing, but only a quarter of the cohort had undergone testing themselves. This study highlights the need for formal educational programs for the healthcare workers at KFMC specifically to improve their knowledge regarding the risk factors and early signs and symptoms of cervical cancer.

Oct 17, 2019

The aim of the present study was to develop a knee size-independent parameter that is suitable for pediatric or small knees and determines the malpositioning of the distal patellar tendon insertion solely utilizing tibial landmarks.  The tibial tubercle posterior cruciate ligament distance (TTPCL)/tibial head diameter (THD) index represents a novel knee size-independent measure describing malpositioning of the distal patellar tendon insertion determined solely by tibial landmarks.

Oct 17, 2019

Researchers attempted to develop a novel rechargeable orthodontic cement with nanoparticles of calcium fluoride (nCaF2) to provide long-term and high levels of F release, and to investigate F recharge and physical and cytotoxic properties. They succeeded in developing it with clinically acceptable enamel SBS, good biocompatibility, and sustained F ion recharge and re-release that were 1.8 folds that of a commercial RMGI.

Recent Articles

Oct 21, 2019

The 46th Annual Williamsburg Conference on Heart Diseases is scheduled to be conducted between December 8-10, 2019 in Williamsburg. This conference will provide both the physiologic and structural bases explanations for cardiac dysfunction and ischemia, and highlight therapeutic means to reverse or slow down pathological progression. 

Oct 21, 2019

In a study using non-invasive tape strips in young children with eczema (or atopic dermatitis), researchers found many molecular signs of immune dysfunction and skin changes that relate to disease activity. These signs (or biomarkers) were present even before eczema was visible and can be used to track disease activity over time. This study was the most comprehensive to date to demonstrate that tape strips can be used in infants and young children instead of painful biopsies to assess early-onset atopic dermatitis on the molecular level

Oct 21, 2019

The 5th NY Masters Course in Comprehensive Endocrine Surgery is scheduled to be conducted between December 12-13, 2019 in New York. This course will provide insight regarding current trends in endocrine surgery, controversies, new technologies, innovations and “scarless” endoscopic surgical techniques will be emphasized.

Clinical Research

Oct 21, 2019

National Institute of Diabetes and Digestive and Kidney Diseases is conducting an Observational study in 99999999 in order to to evaluate, investigate, and follow-up patients suffering from acute and chronic liver disease. The study will focus on understanding diseases affecting the liver.

Oct 21, 2019

Indiana University is conducting an Interventional study in 50 participants in order to quantify the relationship between Y-90 liver therapy and liver damage as very little is known on this subject and present assumptions and calculations of Y-90 administration are based on surgical lobar hepatectomies and external radiation beam therapies.

Oct 21, 2019

China Medical University Hospital is conducting an Interventional trial in 180 participants in order to assess and compare the efficacy of the mixture L acidophilus, B longum and B. bifidum group, Lactobacillus reuteri or placebo group used for the treatment of infantile colic. 

Oct 21, 2019

China Medical University Hospital is conducting an Interventional trial in 180 participants in order to assess and compare the efficacy of the mixture L acidophilus, B longum and B. bifidum group, Lactobacillus reuteri or placebo group used for the treatment of infantile colic. 

Oct 21, 2019

Shaare Zedek Medical Center is conducting an Interventional trial in 80 participants in order to  to compare two alternative modes of administration when enteral acetaminophen is not an option which is common in cases of extremely low birth weight infants as they are on limited or no feeds when PDA closure is determined to be indicated. 

Oct 21, 2019

Mineral trioxide aggregate has been previously FDA approved as an endodontic filler. Its use in vital teeth has demonstrated significant color change post-treatment leaving it ineffective for esthetic use. The new formulation will be tested to see if has the same effect.

Oct 21, 2019

Researchers are conducting an observational study wherein a follow-up telephone interview of the participants of the clinical trial REGATTA exploring the occurrence of urinary tract infections, pyelonephritis within a follow-up period of three months after inclusion is being executed.

Publications

Oct 19, 2019

This atlas provides up-to-date guidance on techniques for immediate loading of dental implants. It highlights key points in immediate implant loading of full-arch prostheses and describes the latest procedures for impression and measurement taking.

Oct 19, 2019

This book is the only text for steroid profile interpretation and contains graphic representations and illustrations. It utilises unique reference data collected over 30 years of clinical practice

Oct 19, 2019

The first book to bring together the innovations gained from positive psychology, psychotherapy, and psychiatry. It is written by global experts in positive mental health.

Oct 19, 2019

This issue of Hand Clinics, guest edited by Drs. Sandeep Sebastin and David Tan, will cover key topics of importance for Soft Tissue Reconstruction for Digital Defects. This issue is one of four selected each year by our series consulting editor, Dr. Kevin Chung. Topics discussed in this issue will include: Vascular Anatomy of the Hand in relation to flaps, Adipofascial Flaps, Transposition and Rotation Flaps, etc.

Oct 19, 2019

This new book covers all aspects of “obesity surgery” under emergency conditions. It describes the frailty of obese patients and the critical care needs in emergency conditions and examines clinical pictures, the indications for surgery and the surgical approach in obese patients in emergency conditions in the general clinical setting and after bariatric surgery.

Oct 16, 2019

The Annals of Pediatric Cardiology is based on the idea of providing a common platform for presenting data and expressing views for members of the following specialties viz. cardiology, cardiac surgery, anesthesiology, intensive care as well as more basic disciplines of pathology, molecular biology and genetics.

Oct 16, 2019

CHEST features the best in peer-reviewed, cutting-edge original research in the multidisciplinary specialties of chest medicine: pulmonary, critical care, and sleep medicine; thoracic surgery; cardiorespiratory interactions; and related disciplines. It is home to highly regarded clinical practice guidelines and consensus statements.

Videos

Oct 20, 2019

A patient returns after having had a crown and filling done 4 days ago that's exquisitely sensitive. Dr. Nick diagnosed (via a process of exclusion coupled with computerized bite analysis) that his slightly altered bite caused a phenomenon known as Frictional Dental Hypersensitivity (FDH).

Oct 20, 2019

Seth P. Lerner, MD, Professor of Urology at Baylor College of Medicine, reviews the results of the Optimized DeLivery of Mitomycin for Primary UTUC Study (OLYMPUS) trial, of which he was the principal investigator. He discusses the difficulty of managing UTUC, the function of UGN-101, and the dramatic results in patient outcomes from this trial.

Oct 20, 2019

The second half of a talk by UCSF Psychiatry chair Matthew W. State, MD, PhD, on the importance of de novo mutations for gene discovery in autism and the rationale for genomic testing in individuals presenting with autism spectrum disorder.

Oct 20, 2019

UCLA endocrine surgeons Michael Yeh, MD, and Masha Livhits, MD give an overview of molecular approaches to diagnosing thyroid cancer, including molecular markets that can be a helpful tool, particularly for indeterminate thyroid nodules.

Case Studies

Oct 20, 2019

A clinical case of an adult patient with a skeletal Class I and clinically deep gingival recession in the mandibular left central incisor. A preadjusted appliance with  slot was placed in both arches. Rectangular arches were used, with the addition of root lingual torque, specifically in the left lower central incisor. Class II and vertical intermaxillary elastics were used throughout the active treatment to obtain intercuspation of the posterior teeth. The orthodontic movement with the application of a localized biomechanics system of forces into the mandibular left central incisor delivered good dental and functional occlusion and, mainly, gingival and periodontal health. 

Oct 18, 2019

This is a a case of thoracic spinal Atypical teratoid rhabdoid tumors in a three-year-old boy who presented with a ten-day history of back pain and progressive weakness of the lower extremities and an inability to walk. The tumor showed characteristic aggressive progression until managed with intensive multimodal therapy to achieve durable long-term remission. 

Oct 18, 2019

 A 43-year-old man in 2014 was diagnosed with oral squamous cell carcinoma involving the tongue. He underwent extensive surgery that involved right tongue cancer resection and reconstruction with a free flap graft from his right forearm. He then was started on chemotherapy and radiation. A biopsy of the mass revealed metastatic squamous cell carcinoma. He was deemed to not be a surgical candidate and continued on palliative chemotherapy. 

Oct 18, 2019

A 50-year-old male with a history of hyperthyroidism, hypertension, and congestive heart failure presented to another hospital with fever and altered mentation. He was found to have pneumonia on imaging and was started on antibiotics. He developed shock complicated by atrial fibrillation with rapid ventricular rate which was treated with amiodarone. The endocrinology team determined he was in thyroid storm. His medical treatment of thyroid storm was aggressively titrated to maximal therapy. But this was followed by transaminitis, respiratory failure requiring intubation, shock requiring vasopressor support, kidney failure requiring continuous renal replacement therapy, and heart failure.