Androgen-deprivation therapy (ADT) with an oral gonadotropin-releasing hormone (GnRH) antagonist rapidly suppressed testosterone and cut the incidence of serious heart events compared to an injectable form of ADT, a phase III trial found.
Junjie Li et.al. conducted a study to assess the efficacy and safety of the addition of capecitabine into the triple-negative breast cancer adjuvant treatment regimen was evaluated. The researchers concluded that capecitabine when added to 3 cycles of docetaxel followed by 3 cycles of a 3-drug anthracycline combination containing capecitabine instead of fluorouracil significantly improved DFS in triple-negative breast cancer without new safety concerns.
Benjin D. Facer et.al. conducted a study to assess the efficacy of Intraoperative radiation therapy using electronic brachytherapy. The researchers concluded that Intraoperative radiation therapy is a convenient and well-tolerated treatment option for the appropriately selected woman undergoing partial breast irradiation. Rates of seroma formation are similar to rates reported for multiple fraction catheter-based systems.
William H. Smith et.al. conducted a study to assess the safety of nivolumab as Nivolumab has been demonstrated to be effective for the treatment of unresectable hepatocellular carcinoma. The researchers concluded that Combination radiation therapyand nivolumab is generally safe in the management of unresectable hepatocellular carcinoma with a low rate of serious adverse events. Prospective trials investigating the efficacy of combination nivolumab and radiation therapy are warranted.
Suguru Uemura et.al. conducted a study to review the clinical records of the patients diagnosed with osteosarcoma at our institute between 2004 and 2018 who received high-dose chemotherapy followed by autologous stem cell transplantation. The researchers concluded that High-dose chemotherapy followed by autologous stem cell transplantation might be effective for poor responders in osteosarcoma.
The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.
This research study is being done to understand how patients with chronic cancer pain take their long-acting opioid medications and to develop an intervention to enhance cancer pain management.
Christopher G. Brennan-Jones et.al. identified specific strategies which have shown effectiveness in reducing workplace noise. These include implementation of stricter legislation and also stress upon the need for training in the proper use of earplugs and earmuffs so as to reduce noise exposure to safe levels.
Advance in Cancer Prevention addresses all types of cancer, how cancer forms in the body, and their prevention. It focuses on Cancer Vaccines, Chemotherapy, Radioactive Iodine Therapy, Breast Reconstruction Surgery, Mammography, Chemoprevention, aromatase inhibitors, Scintimammography, Oncoplastic surgery, Sumoylation, Dietary Supplements, Cancer Screening, Cancer and Nutrition, Exercise and Cancer, Alternative Cancer Medicines, Stem cell transplants for cancer prevention, Naturopathic Treatments, Clinical Naturopathy, Cancer Prevention from nuts.
This highly respected and frequently cited journal is a prime source of information in the area of fetal and neonatal research. Original papers present research on all aspects of neonatology, fetal medicine and developmental biology. These papers encompass both basic science and clinical research including randomised trials, observational studies and epidemiology.
Promoting rational therapy within the discipline of cardiology, the American Journal of Cardiovascular Drugs covers all aspects of the treatment of cardiovascular disorders, particularly the place in therapy of newer and established agents. Via a program of reviews and original clinical research articles, the journal addresses major issues relating to treatment of these disorders, including the pharmacology, efficacy and adverse effects of the major classes of drugs; information on newly developed drugs and drug classes.
Rimma Shaposhnikov, MD UCLA gastroenterologist and Natalie Manitius, MPH, RDN, UCLA GI Dietitian, discuss which screening modalities work for colon cancer, how often one needs to get screened when a person can stop colonoscopies and dietary tips to prevent colon cancer.
Dr. Gonzalo Sapisochin presents his research using living liver transplantation as a treatment for patients with colorectal cancer that has spread to the liver. Liver transplantation is frequently used as a curative treatment for selected patients with the most common liver cancer, hepatocellular carcinoma. Dr. Sapisochin’s study is expanding liver transplantation to patients with colorectal cancer which has spread to the liver. Colorectal cancer is diagnosed in 1.8 million people every year and it is estimated that in approximately 50 percent of these cases, cancer will spread to the liver. "We think that pre-transplant chemotherapy, careful monitoring of tumors, and living donation will give our patients better results," says Dr. Sapisochin.
Kamal Bhsual presented a talk on Primary Hyperparathyroidism with an objective of understanding the etiology, pathophysiology, manifestations, investigations and the management. The speaker has also discussed about the cases of Normocalcemic Primary Hyperparathyroidism and the points to consider under such instances.
Dr. Patrick Kamath presented a talk on liver in cases of Cardiac diseases. The speaker has discussed in detail about its symptomatolgy, progression of symptoms, identification of diagnostic signs, recommended investigations and lastly current updates in the treatment strategies of the same.
Isabella Aquila et.al. describe a case of Sudden death due to Takayasu’s arteritis and how histopathology came in handy by revealing eosinophilia in the aortic wall, consistent with a vasculitis such as Takayasu’s arteritis as the autopsy only showed sclerosis of the thoracic aorta, abdominal aorta and coronary arteries.
Shuquan Zhao et.al. presented a case of a a 21-year-old woman diagnosed with “acute gastroenteritis” who expired 4 days later. Autopsy findings revealed an inflammatory polypous embolic located at 1.0 cm from the left anterior descending branch. To find the real cause of this embolus, virus detection was performed through RT-PCR, however the findings were negative.
During a craniotomy, hemostatic materials such as oxidized cellulose and cotton pads, commonly used to control bleeding, may cause a granulomatous reaction that may produce space-occupying mass lesions termed textiloma (or gossypiboma). Nicola Montemurro et al presents the case of a 46-year-old female who underwent a right frontotemporal craniotomy and surgical removal of an intraparenchymal cerebral hemorrhage. The patient developed a textiloma during the postoperative period that led to seizures.
Follicular lymphoma is an indolent non-Hodgkin lymphoma that is most prevalent among the elderly population. An 82-year-old female with refractory follicular lymphoma achieved a partial response with idelalisib treatment, Despite experiencing two incidences of the psoriasis-like rash during the treatment the patient was able to restart treatment successfully and maintain a continued partial response.