News

Jun 17, 2019

The results of a pilot study suggest that electrostimulation of one of the nerves connecting the brain to the body (the vagus nerve), could provide a novel treatment approach for patients with rheumatoid arthritis. In this study, a novel miniaturized neurostimulator called a MicroRegulator was implanted into 14 patients with rheumatoid arthritis who had failed on at least two biologics or targeted oral therapies with different mechanisms of action. Patients were randomized to three groups who were either placebo, stimulated once daily, or stimulated four times a day for 12 weeks.

Jun 17, 2019

Using a new blood test that's in development researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection. The researchers developed the test to detect levels of DNA in the blood from HPV-linked oropharyngeal squamous cell carcinoma tumors. Studies are ongoing to see if the test can be used to monitor patients' response to treatment with radiation and chemotherapy.

Jun 17, 2019

In a recent meta-analysis of 24 studies, Boone and a team of researchers considered 313 cases of borderline resectable pancreatic cancer that physicians treated with FOLFIRINOX. They analyzed the patients' overall survival rates. They also evaluated how frequently tumors shrank enough to be surgically removed. The team found that FOLFIRINOX prolonged patients' lives, on average, and made surgery possible in more instances. 

Journal Abstracts

Jun 14, 2019

This study examined whether individuals undergoing total hip arthroplasty who are self-rated as “highly active”, demonstrated higher pre-operative activity levels than others. The positive correlation between subjective and objective measures of mobility increase our confidence in the latter as a valid indicator of the patient's preoperative activity level.

Jun 14, 2019

The study aimed to assess the status of vitamin D for patients with pityriasis alba. 44 patient diagnosed with pityriasis alba were enrolled and the second group of 44 controls was involved in our study. Serum levels of circulating 25 (OH) D were measured. Study findings conclude none of the cases had sufficient serum level; the level ranged between 8.1-27.3 ng/ml. The patients had lower circulating vitamin D levels than controls.

Jun 14, 2019

This retrospective, longitudinal, and repeated-measures study assess vestibular aqueduct (VA)  morphology and frequency-specific hearing thresholds with sex as the primary predictor of interest. Females seem to have greater enlargement of the vestibular aqueduct, this difference does not extend to hearing loss. Therefore, study results indicate that criteria for enlargement of the vestibular aqueduct (EVA)  diagnoses may benefit from re-evaluation. 

Recent Articles

Jun 17, 2019

Shenzhen Geno-Immune Medical Institute is conducting a Phase I/II clinical trial of gene transfer for treating Beta-thalassemia using a self-inactivating lentiviral vector to functionally correct the defective gene(s) in 20 participants. The objectives are to evaluate the safety and efficacy of the gene transfer clinical protocol.

Jun 17, 2019

Universidade Federal Fluminense is conducting an Observational study in 200 participants in order to  propose cervicothoracic transcutaneous electrical nerve stimulation (TENS) as a non-pharmacological therapy to attenuate cardiac sympathetic overdrive in patients with heart failure.

Jun 17, 2019

Barts & The London NHS Trust is conducting an Observational study in 150 participants in order to identify new predisposition genes for endocrine tumours. The focus initially is on pituitary adenomas including growth hormone-secreting tumors (somatotrophinomas) and prolactin secreting tumours (prolactinomas), but the authors extended work to other pituitary tumour cases/families.

Clinical Research

Jun 17, 2019

Universidade Federal Fluminense is conducting an Observational study in 200 participants in order to  propose cervicothoracic transcutaneous electrical nerve stimulation (TENS) as a non-pharmacological therapy to attenuate cardiac sympathetic overdrive in patients with heart failure.

Jun 17, 2019

Barts & The London NHS Trust is conducting an Observational study in 150 participants in order to identify new predisposition genes for endocrine tumours. The focus initially is on pituitary adenomas including growth hormone-secreting tumors (somatotrophinomas) and prolactin secreting tumours (prolactinomas), but the authors extended work to other pituitary tumour cases/families.

Jun 17, 2019

Alfasigma S.p.A. is conducting an Interventional study in 882 participants in order to evaluate the safety and efficacy of two different doses of a delayed release formulation of rifaximin, versus placebo, for the prevention of recurrence of acute diverticulitis and diverticular complications in patients with a recent episode of acute diverticulitis. 

Jun 17, 2019

Alfasigma S.p.A. is conducting an Interventional study in 882 participants in order to evaluate the safety and efficacy of two different doses of a delayed release formulation of rifaximin, versus placebo, for the prevention of recurrence of acute diverticulitis and diverticular complications in patients with a recent episode of acute diverticulitis. 

Jun 17, 2019

HaEmek Medical Center, Israel is conducting an Observational study in 7000 participants in order to to determine whether there is a need for preparative fasting prior to contrast-enhanced computed tomography (CT)/ 

Jun 17, 2019

The removed wisdom teeth and tissue are thrown away as medical waste. Oral health researchers want to collect teeth and tissue for research and encourage dentists at the National Institutes of Health to improve their skills in oral surgery. This study will collect the teeth and tissue of people who need to have oral surgery to remove their wisdom teeth.

Jun 17, 2019

Investigators aim to evaluate the overall response rate (ORR) of pemigatinib as a monotherapy in the treatment of metastatic or surgically unresectable urothelial carcinoma harboring FGF/FGFR alterations.

Publications

Jun 12, 2019

Pediatric Radiology informs its readers of new findings and progress in all areas of pediatric imaging and in related fields. This is achieved by a blend of original papers, and reviews describing the present state of knowledge in a particular topic. Contents include advances in technology, methodology, apparatus and auxiliary equipment are presented, and modifications of standard techniques.

Jun 12, 2019

Academic Pediatrics, the official journal of the Academic Pediatric Association, is a peer-reviewed publication whose purpose is to strengthen the research and educational base of academic general pediatrics. The journal provides leadership in pediatric education, research, patient care and advocacy. 

Jun 12, 2019

 European Journal of Preventive Cardiology is a  peer-reviewed journal of the European Association of Preventive Cardiology (EAPC) and the world's leading journal in preventive cardiology, playing a pivotal role in reducing the global burden of cardiovascular disease. Addresses the causes and prevention of cardiovascular disease, as well as cardiovascular rehabilitation and exercise physiology.

Jun 12, 2019

Hormones and Behavior publishes original research articles, reviews and special issues concerning hormone-brain-behavior relationships, broadly defined. The journal's scope ranges from laboratory and field studies concerning neuroendocrine as well as endocrine mechanisms controlling the development or adult expression of behavior to studies concerning the environmental control and evolutionary significance of hormone-behavior relationships.

Jun 11, 2019

Annals of Allergy, Asthma & Immunology is a scholarly medical journal published monthly by the American College of Allergy, Asthma & Immunology. The purpose of Annals is to serve as an objective evidence-based forum for the allergy/immunology specialist to keep up to date on current clinical science (both research and practice-based) in the fields of allergy, asthma, and immunology. The emphasis of the journal will be to provide clinical and research information that is readily applicable to both the clinician and the researcher.

 

Jun 11, 2019

This issue of the Atlas of the Oral and Maxillofacial Surgery Clinics of North America focuses on Sleep Surgery and is edited by Dr. Stanley Liu. Articles will include Upper Airway (Hypoglossal Nerve) Stimulation; Functional Drug-Induced Sleeping Endoscopy; Genioglossus and Genioplasty Advancement; Maxillomandibular Advancement: Stanford Method; Pediatric Sleep Surgery: Skeletal Procedures; Maxillomandibular Advancement with TMJ Replacement etc.

Jun 11, 2019

Best Practice & Research: Clinical Rheumatology keeps the clinician or trainee informed of the latest developments and current recommended practice in the rapidly advancing fields of musculoskeletal conditions and science.  The series provides a continuous update of current clinical practice. It is a topical serial publication that covers the spectrum of musculoskeletal conditions in a 4-year cycle.

Videos

Jun 14, 2019

Watch UCLA gastroenterologist Dr. Lisa Lin, MD discuss the symptoms of acid reflux, how to test for it and the available treatment options.

Jun 14, 2019

 

 

Watch Dr. Itzhak Fried present "Laser Ablation for Epilepsy" at UCLA Neurosurgery Update 2019. UCLA Neurosurgery at the David Geffen School of Medicine at UCLA presented its second annual comprehensive update on emerging diagnostic and treatment modalities for diseases of the brain and spine, drawing upon the department's world-class expertise in each sub-specialty.

Jun 14, 2019

Watch Dr. Harvey Fishman, MD, Ph.D. discuss the role of intense pulsed light therapy to treat OSD. Eradicating Demodex helps keep the ocular microbiome healthy. 

Jun 14, 2019

This webinar presents the infection risks associated with different vascular access types. Discussion includes strategies and recommendations for successful catheter reduction to prevent bloodstream infections. It includes a presentation on “Incident Vascular Access and Risk of Bloodstream Infection Among New ESRD Patients Receiving Hemodialysis” followed by a conversation about achieving optimal vascular access for patient safety.

Case Studies

Jun 14, 2019

An African American woman presented with neurologic-type symptoms. The appearance of the ground-glass opacities in this case is unique, appearing as discrete well-defined mass-like ground-glass opacities in a peribronchovascular distribution without additional parenchymal findings typically seen in sarcoidosis.

Jun 14, 2019

A 17-year-old boywas hospitalized with a history of recurrent abdominal pain, fever, and dark-colored urine. Laboratory tests revealed anemia, thrombocytopenia, and elevated inflammatory markers. Urinalysis was positive for protein and red blood cells, too many to be counted.  Abdominal computed tomography showed a segment of the small bowel with wall thickening and signs of possible microperforation. Flow cytometry detected deficiency of CD59 leading to the diagnosis of Paroxysmal Nocturnal Hemoglobinuria. 

Jun 14, 2019

An 83-year-old male had been working as a coal miner and was diagnosed with silicosis at the age of 63. Because he had experienced repeated pericardial effusions, he was referred for a surgical pericardial biopsy to elucidate the cause of his repeated pericardial effusion and to perform pericardial fenestration. Thoracoscopic surgery was performed. The pericardium was resected, and a drain was placed in the left thoracic cavity. Histopathological examination revealed the pericardial degeneration due to silicosis, suggesting that pericarditis and pericardial effusion are related to silicosis.

Jun 14, 2019

A 73-year-old female patient with metastatic thyroid papillary carcinoma was treated with total thyroidectomy. The operation was followed by four radioiodine therapies over a period of 6 years. At 6 years she developed lung metastasis without radioiodine uptake, one solitary liver metastasis and one solitary right renal metastasis. One year after the first diagnosis of radioiodine resistant lung metastasis the lung metastasis showed progression according to RECIST criteria.