News

Jun 17, 2019

Using a new blood test that's in development researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection. The researchers developed the test to detect levels of DNA in the blood from HPV-linked oropharyngeal squamous cell carcinoma tumors. Studies are ongoing to see if the test can be used to monitor patients' response to treatment with radiation and chemotherapy.

Jun 17, 2019

A hair-sized probe that can measure key indicators of tissue damage deep in the lung has been developed by scientists. A team of scientists developed the probe, which comprises an optical fiber about 0.2mm in diameter that holds 19 sensors. Each sensor can measure different indicators in tissues, such as acidity and oxygen levels, which provide important information on the body's reaction to disease processes.

Jun 17, 2019

The results of a pilot study suggest that electrostimulation of one of the nerves connecting the brain to the body (the vagus nerve), could provide a novel treatment approach for patients with rheumatoid arthritis. In this study, a novel miniaturized neurostimulator called a MicroRegulator was implanted into 14 patients with rheumatoid arthritis who had failed on at least two biologics or targeted oral therapies with different mechanisms of action. Patients were randomized to three groups who were either placebo, stimulated once daily, or stimulated four times a day for 12 weeks. At the end of the study, the patients who received once-daily stimulation were shown to have a better response than those on four-times-daily stimulation.

Journal Abstracts

Jun 14, 2019

The study aimed to assess the status of vitamin D for patients with pityriasis alba. 44 patient diagnosed with pityriasis alba were enrolled and the second group of 44 controls was involved in our study. Serum levels of circulating 25 (OH) D were measured. Study findings conclude none of the cases had sufficient serum level; the level ranged between 8.1-27.3 ng/ml. The patients had lower circulating vitamin D levels than controls.

Jun 14, 2019

This study is to determine the safety and preliminary efficacy of selective combination targeted therapy for BRAF V600E–mutant metastatic colorectal cancer (mCRC) in the safety lead-in phase of the open-label, randomized, three-arm, phase III BEACON Colorectal Cancer trial. In the safety lead-in, the safety and tolerability of the encorafenib, binimetinib, and cetuximab regimen are manageable and acceptable for initiation of the randomized portion of the study. The observed efficacy is promising compared with available therapies and, if confirmed in the randomized portion of the trial, could establish this regimen as a new standard of care for previously treated BRAF V600E–mutant mCRC.

Jun 14, 2019

This study examined whether individuals undergoing total hip arthroplasty who are self-rated as “highly active”, demonstrated higher pre-operative activity levels than others. The positive correlation between subjective and objective measures of mobility increase our confidence in the latter as a valid indicator of the patient's preoperative activity level.

Recent Articles

Jun 17, 2019

By Using sound vibrations and pulses of near-infrared light, a Rutgers University scientist has developed a new "virtual biopsy" device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel. The first-of-its-kind experimental procedure, called vibrational optical coherence tomography (VOCT), creates a 3-D map of the legion's width and depth under the skin with a tiny laser diode. 

Jun 17, 2019

The '13th Annual Conference of the International Liver Cancer Association (ILCA)' is schduled to be conducted between September 20-22, 2019 in Chicago. This 3-day cutting-edge international multidisciplinary forum will provide liver cancer specialists, clinical, translational and basic researchers and allied health professionals with updates in the latest innovations in liver cancer research and patient care.

Jun 17, 2019

Annals of Surgical Oncology is one of the leading journals in Oncology and Surgery.  Annals of Surgical Oncology is the official journal of the Society of Surgical Oncology. Annals benefits surgeons, oncologists, hematologists, radiologists, general practitioners, pathologists, researchers, academicians, and other clinical professionals interested in all aspects of the surgical treatment of cancer.

 

Clinical Research

Jun 17, 2019

Universidade Federal Fluminense is conducting an Observational study in 200 participants in order to  propose cervicothoracic transcutaneous electrical nerve stimulation (TENS) as a non-pharmacological therapy to attenuate cardiac sympathetic overdrive in patients with heart failure.

Jun 17, 2019

Barts & The London NHS Trust is conducting an Observational study in 150 participants in order to identify new predisposition genes for endocrine tumours. The focus initially is on pituitary adenomas including growth hormone-secreting tumors (somatotrophinomas) and prolactin secreting tumours (prolactinomas), but the authors extended work to other pituitary tumour cases/families.

Jun 17, 2019

Alfasigma S.p.A. is conducting an Interventional study in 882 participants in order to evaluate the safety and efficacy of two different doses of a delayed release formulation of rifaximin, versus placebo, for the prevention of recurrence of acute diverticulitis and diverticular complications in patients with a recent episode of acute diverticulitis. 

Jun 17, 2019

Alfasigma S.p.A. is conducting an Interventional study in 882 participants in order to evaluate the safety and efficacy of two different doses of a delayed release formulation of rifaximin, versus placebo, for the prevention of recurrence of acute diverticulitis and diverticular complications in patients with a recent episode of acute diverticulitis. 

Jun 17, 2019

HaEmek Medical Center, Israel is conducting an Observational study in 7000 participants in order to to determine whether there is a need for preparative fasting prior to contrast-enhanced computed tomography (CT)/ 

Jun 17, 2019

Investigators aim to evaluate the overall response rate (ORR) of pemigatinib as a monotherapy in the treatment of metastatic or surgically unresectable urothelial carcinoma harboring FGF/FGFR alterations.

Jun 17, 2019

A double-blind, placebo-controlled, randomized withdrawal, multicenter clinical trial will be evaluating the safety and efficacy of cariprazine in the treatment of Bipolar I disorder patients whose current episode is manic or depressive with or without mixed features.

Publications

Jun 17, 2019

Annals of Surgical Oncology is one of the leading journals in Oncology and Surgery.  Annals of Surgical Oncology is the official journal of the Society of Surgical Oncology. Annals benefits surgeons, oncologists, hematologists, radiologists, general practitioners, pathologists, researchers, academicians, and other clinical professionals interested in all aspects of the surgical treatment of cancer.

 

Jun 12, 2019

Academic Pediatrics, the official journal of the Academic Pediatric Association, is a peer-reviewed publication whose purpose is to strengthen the research and educational base of academic general pediatrics. The journal provides leadership in pediatric education, research, patient care and advocacy. 

Jun 12, 2019

 European Journal of Preventive Cardiology is a  peer-reviewed journal of the European Association of Preventive Cardiology (EAPC) and the world's leading journal in preventive cardiology, playing a pivotal role in reducing the global burden of cardiovascular disease. Addresses the causes and prevention of cardiovascular disease, as well as cardiovascular rehabilitation and exercise physiology.

Jun 12, 2019

Hormones and Behavior publishes original research articles, reviews and special issues concerning hormone-brain-behavior relationships, broadly defined. The journal's scope ranges from laboratory and field studies concerning neuroendocrine as well as endocrine mechanisms controlling the development or adult expression of behavior to studies concerning the environmental control and evolutionary significance of hormone-behavior relationships.

Jun 12, 2019

Pediatric Radiology informs its readers of new findings and progress in all areas of pediatric imaging and in related fields. This is achieved by a blend of original papers, and reviews describing the present state of knowledge in a particular topic. Contents include advances in technology, methodology, apparatus and auxiliary equipment are presented, and modifications of standard techniques.

Jun 11, 2019

Burns aims to foster the exchange of information among all engaged in preventing and treating the effects of burns. The journal focuses on clinical, scientific and social aspects of these injuries and covers the prevention of the injury, the epidemiology of such injuries and all aspects of treatment including development of new techniques and technologies and verification of existing ones. Regular features include clinical and scientific papers, state of the art reviews and descriptions of burn-care in practice.

 

Jun 11, 2019

Annals of Allergy, Asthma & Immunology is a scholarly medical journal published monthly by the American College of Allergy, Asthma & Immunology. The purpose of Annals is to serve as an objective evidence-based forum for the allergy/immunology specialist to keep up to date on current clinical science (both research and practice-based) in the fields of allergy, asthma, and immunology. The emphasis of the journal will be to provide clinical and research information that is readily applicable to both the clinician and the researcher.

 

Videos

Jun 14, 2019

Watch UCLA gastroenterologist Dr. Lisa Lin, MD discuss the symptoms of acid reflux, how to test for it and the available treatment options.

Jun 14, 2019

 

 

Watch Dr. Itzhak Fried present "Laser Ablation for Epilepsy" at UCLA Neurosurgery Update 2019. UCLA Neurosurgery at the David Geffen School of Medicine at UCLA presented its second annual comprehensive update on emerging diagnostic and treatment modalities for diseases of the brain and spine, drawing upon the department's world-class expertise in each sub-specialty.

Jun 14, 2019

Watch Dr. Harvey Fishman, MD, Ph.D. discuss the role of intense pulsed light therapy to treat OSD. Eradicating Demodex helps keep the ocular microbiome healthy. 

Jun 14, 2019

This webinar presents the infection risks associated with different vascular access types. Discussion includes strategies and recommendations for successful catheter reduction to prevent bloodstream infections. It includes a presentation on “Incident Vascular Access and Risk of Bloodstream Infection Among New ESRD Patients Receiving Hemodialysis” followed by a conversation about achieving optimal vascular access for patient safety.

Case Studies

Jun 14, 2019

A 17-year-old boywas hospitalized with a history of recurrent abdominal pain, fever, and dark-colored urine. Laboratory tests revealed anemia, thrombocytopenia, and elevated inflammatory markers. Urinalysis was positive for protein and red blood cells, too many to be counted.  Abdominal computed tomography showed a segment of the small bowel with wall thickening and signs of possible microperforation. Flow cytometry detected deficiency of CD59 leading to the diagnosis of Paroxysmal Nocturnal Hemoglobinuria. 

Jun 14, 2019

An 83-year-old male had been working as a coal miner and was diagnosed with silicosis at the age of 63. Because he had experienced repeated pericardial effusions, he was referred for a surgical pericardial biopsy to elucidate the cause of his repeated pericardial effusion and to perform pericardial fenestration. Thoracoscopic surgery was performed. The pericardium was resected, and a drain was placed in the left thoracic cavity. Histopathological examination revealed the pericardial degeneration due to silicosis, suggesting that pericarditis and pericardial effusion are related to silicosis.

Jun 14, 2019

A 73-year-old female patient with metastatic thyroid papillary carcinoma was treated with total thyroidectomy. The operation was followed by four radioiodine therapies over a period of 6 years. At 6 years she developed lung metastasis without radioiodine uptake, one solitary liver metastasis and one solitary right renal metastasis. One year after the first diagnosis of radioiodine resistant lung metastasis the lung metastasis showed progression according to RECIST criteria. 

Jun 14, 2019

A 60-year-old female presented with constant severe epigastric pain associated with nausea, vomiting, and anorexia for one day. She had no past medical history of alcohol use or hypertriglyceridemia and was s/p cholecystectomy in the distant past. Symptoms had begun three days after starting metronidazole forClostridium difficile colitis. Lipase was > 396, and CT abdomen revealed peripancreatic fat stranding. She was diagnosed with AP, metronidazole was suspected to be responsible and hence stopped, and supportive management initiated. Her symptoms improved rapidly, and pancreatic enzymes normalized within 2 days.