Lobular Involution-Based Response to Antiendocrine Therapy for Women with Breast Atypical Hyperplasia

Mayo Clinic
24 Jun, 2019 ,

Mayo Clinic has undertaken a study to perform a quantitative measure of lobular involution (qLI) from breast biopsy samples obtained at baseline (surgery) and 12 months or at time of study discontinuation. The study will determine breast density (MMG) and correlate with qLI. The study will also determine the influence of chemoprevention therapies such as tamoxifen and letrozole on qLI.