Research Desk

Dec 04, 2020

Synnøve Gjelsten Mortensen et.al. report a classic case of epipericardial fat necrosis (EFN) in a 22-year-old male who presented to the ER with left-sided chest pain and shortness of breath. The patient underwent radiologic examinations and findings consistent with EFN with associated thickening of the adjacent pericardium and associated pleural effusion and atelectasis were observed. The patient was started on NSAID therapy which led to the resolution of the symptoms.

Dec 04, 2020

The elevated risk of developing asthma among children delivered by cesarean section could be attributed to differences in their gut microbiome. The passage through the birth canal ensures that the baby has the beneficial germs. During the time that the normal microbiome develops in the baby, they become more at risk for developing diseases like asthma. By the age of 6, the risk for developing asthma is 13% in children born via C-section whereas it is 6% for those born vaginally. Researchers are of the opinion that ensuring that the children achieve a normal gut microbiota could go a long way in lowering the risk of asthma.

Dec 04, 2020

According to NIH new recommendations for the diagnosis, management and treatment of asthma in adolescents and adults, the first updates to federal comprehensive asthma guidelines in more than a decade. “The 2020 focused updates to the asthma management guidelines are intended to help primary care providers, specialists and patients work together to make decisions about the optimal management of their asthma,” James Kiley, PhD, director of the division of lung diseases at NHLBI, part of the NIH, said during a media telebriefing.

Dec 04, 2020

According to a study published in JAMA Network Open, results from a national, cross-sectional survey showed a decrease in e-cigarette use among teens and young adults during the COVID-19 pandemic. Since the beginning of the COVID-19 pandemic, 1,198 of the 2,125 (56.4%) e-cigarette users included in the study reported changing the amount of their use 388 (32.4%) quit and 422 (35.3%) reduced the amount of nicotine intake.

Dec 04, 2020

It has come to notice that  RA drug baricitinib, a Janus kinase 1/2 inhibitor, might be beneficial in controlling the cytokine storm of hyperinflammation that can follow severe SARS-CoV-2 infections and lead to lung damage and acute respiratory distress syndrome is the leading cause of death from the virus. Artificial intelligence, provided by the London-based firm BenevolentAI, was used to sift through a huge repository of structured medical information to identify drugs that might block the SARS-CoV-2 infection process.

Dec 04, 2020

H.Y. AbuNurah et.al. conducted a study to purpose of this review was to assess the quality of literature available on using extra-diaphragmatic sEMG as an assessment technique of respiratory responses during mechanical ventilation. The researchers concluded that Although it appears to be a valid and applicable tool, there is a scarcity of literature that directly demonstrates the diagnostic accuracy of sEMG of extra-diaphragmatic muscles in monitoring respiratory mechanics and respiratory drive or sensation during mechanical ventilation assistance across wide populations and conditions.

Dec 04, 2020

Julyan Al Fori et.al. presented a case of haemoptysis, three months postradiofrequency ablation (i.e., late complication) secondary to pulmonary vein occlusion that was diagnosed by computed tomography angiogram, which showed occlusion of 2 out of 4 native pulmonary veins. The cause of haemoptysis in this patient was pulmonary vein occlusion, secondary to radiofrequency ablation, as demonstrated in the computed tomography angiogram.

Dec 04, 2020

The retrospective cohort study carried out by Jan Niederdöckl et.al attempts to develop a risk score using clinical and routine laboratory variables to predict the probability of spontaneous conversion to sinus rhythm in hemodynamically stable patients with non-permanent symptomatic atrial fibrillation. Such a scoring could be a guide for cardioversion decisions and avoid the risk of overtreatment. The study was done on 2426 patients and multivariable analysis was performed and the clinical usefulness of the score was determined using decision curve analysis. The newly developed score, ReSinus, was found to show good calibration, discrimination and usefulness.

Dec 04, 2020

Researchers at the National Institute for Allergies and Infectious Diseases (NIAID), the co-developers of Moderna vaccine, have studied the immune response of 34 adult participants from the first stage of a clinical trial of the vaccine. It has been found that the vaccine is capable of mounting an immune response for a period of 3 months after the second dose. It was also seen that a reasonably strong immune response was seen in patients up to 70 years of age.

Dec 04, 2020

Jumpei Takamatsu et.al. report the case of a 70-year-old woman with a history of uterine fibroids who presented with cardiopulmonary arrest. Abdominal CT revealed ascites accumulation and fluid-containing uterine fibroids. Owing to the purulent nature of the ascites, intraperitoneal infection was suspected and an emergency laparotomy was performed. Twelve hours later she underwent a second surgery to ascertain the origin of the infection and a pore at the top of the fibroid with continuous discharge of pus was detected in the uterus and hence a hysterectomy was performed.