Research Desk

Feb 12, 2019

Massachusetts General Hospital Pediatric Epilepsy Brain Imaging Research Study is recruiting children with benign childhood epilepsy (benign rolandic epilepsy, benign epilepsy with centrotemporal spikes) and healthy children without epilepsy, aged 6 years old and above, for a non-invasive brain imaging study to identify markers to predict ongoing seizure risk or cognitive effects in childhood epilepsy using Magnetic Resonance Imaging (MRI), Magnetoencephalography (MEG), electroencephalography (EEG), and neuropsychological testing

Feb 12, 2019

Treatment with ACTHAR Gel will result in a reduction of ocular inflammation in patients with active ocular sarcoidosis that requires systemic immunosuppressant therapy (hypothesis)

 

Feb 12, 2019

The aims of this study are: 1) to identify genes that play a role in human pubertal development and reproduction, 2) to characterize the phenotypic spectrum of patients with these gene defects, and 3) to discern the mode of inheritance for disorders caused by these gene defects. We are specifically interested in genes that cause Kallmann syndrome, idiopathic hypogonadotropic hypogonadism (IHH), precocious (early) puberty, and delayed puberty. Individuals do not have to travel to Boston to participate in this study.

 

Feb 12, 2019

This study is testing a medication, called hydroxychloroquine (HCQ) to assess safety and effectiveness to prevent individuals at risk of type 1 diabetes (T1D) from progressing to type 1 diabetes. HCQ is approved by the U.S. Food and Drug Administration as a treatment for malaria, lupus, and rheumatoid arthritis. HCQ has been used extensively for treatment of autoimmune disease in adults, children, and during pregnancy. This medication has not previously been studied as a treatment to prevent T1D. The goal of this study is to learn if HCQ can help prevent or delay progression from normal glucose tolerance (Stage 1) to abnormal glucose tolerance (Stage 2) or type 1 diabetes (Stage 3). The study involves 5 visits in the first 6 months, then 1 visit every 6 months for the remainder of the study.

 

Feb 12, 2019

A multicentre two-group parallel single-blind (outcome assessor) randomized controlled trial (RCT). A cost-effectiveness study alongside a clinical trial using a payer and societal perspective to study the cost-effectiveness of geriatric assessment and management compared to usual care will be conducted. Participants allocated to the control group will receive usual oncology care. Participants allocated to the intervention group will receive a comprehensive geriatric assessment and management in addition to their usual oncology care. The intervention will take 6 months to be completed. Total study follow-up will be 12 months for each participant.

Feb 11, 2019

In this study, researchers are trying to find out if axillary reverse mapping (ARM) with lympho-venous bypass (LVB) in patients undergoing an axillary lymph node dissection reduces the rate and severity of post-operative lymphedema of the arm.

Feb 11, 2019

This study intends to establish an imaging protocol and investigate the utility of contrast-enhanced ultrasound (CEUS) in the diagnostic work-up of soft tissue hematoma as an ionizing radiation-free alternative to computed tomography (CT) that can be used independent from the kidney function of the patient.

Feb 11, 2019

American Association of Clinical Endocrinologists is all set to conduct its 28th Annual Meet at Los Angeles Convention Center & JW Marriot between April 24-28, 2019. This congress shall cover current medical and technological in the field of Endocrinology. 

Feb 11, 2019

This interventional study by the Boston University's Henry M. Goldman School of Dental Medicine aims to explore use of the TENS to alleviate pain and discomfort at the oral mucosal site where the patient will receive a local anesthetic injection.

Feb 11, 2019

This interventional study by the Boston University's Henry M. Goldman School of Dental Medicine aims to explore use of the TENS to alleviate pain and discomfort at the oral mucosal site where the patient will receive a local anesthetic injection.