Research Desk

Apr 19, 2019

A 14-year-old adolescent with short stature and delayed puberty, was admitted in a Paediatric Endocrinology outpatient clinic. His familial target height was on percentile 3–10.  After a careful investigation, he was found to have a 45,X/46,X,idic(Y)(p11.32) mosaicism. 

Apr 19, 2019

A 38-year-old with sickle cell disease-associated Pulmonary hypertension and acute chest syndrome was successfully managed with inhaled and oral pulmonary vasodilators in the setting of persistent elevations in pulmonary vascular resistance leading to acute RV failure and cardiogenic shock. 

Apr 19, 2019

A 35-year-old patient was admitted to endocrinology outpatient department with complaint of pain in the neck. Physical examination revealed 2 cm nodule on the thyroid right lobe. Serum thyroid hormone levels were within normal range. Ultrasonography revealed a 23x15 mm hypoechoic nodule with micro calcifications and cystic areas on the right lobe. 

Apr 19, 2019

 A 63-year-old male with severe iron deficiency anemia on biweekly intravenous iron infusions and weekly packed red blood cell transfusions presented with melena over several months. Upper endoscopy demonstrated a clean-based gastric body ulcer and nonbleeding gastric varices. Histology of the gastric ulcer was suggestive of iron-induced gastric mucosal injury.

Apr 19, 2019

 A 51-year-old man came with Rasmussen’s aneurysm that was successfully treated by proximal coil blocking with n-butyl-2-cyanoacrylate (NBCA) injection via the pulmonary artery alone. With proximal coil blocking, a sufficient amount of NBCA could be injected without unintended reflux of the NBCA cast to the proximal pulmonary artery. 

Apr 19, 2019

A 31-year-old male with a history of OCD had orofacial dyskinesia with prominent tongue dystonia and tongue protrusion on feeding. The patient exhibited involuntary self-mutilating behavior with biting of tongue and cheeks and severe bruxism. Sequencing of the VPS13A-gene revealed a novel homozygous mutation (c.1186del) with subsequent nonsense-mediated RNA-decay confirming the diagnosis of chorea-acanthocytosis. The patient’s parents were both heterozygous for the mutation.

Apr 19, 2019

62-year-old man underwent resection of a hepatic tumor arising after gastric GIST surgery that was resistant to imatinib and sunitinib. A 40-mm tumor in the left lobe of the liver and three small nodules in the right lobe were detected. Hepatic left lobectomy and partial resections for three lesions were performed. According to the histopathological and immunohistochemical findings and c-kit gene mutations analysis, the main tumor was diagnosed as a PLMS.

Apr 19, 2019

This case series describes two individuals with appendicitis presenting to the ED. One case is of a patient with Amyand’s hernia and another case is a patient with De Garengeot’s hernia with an adjacent abscess. Both individuals were managed with appendectomy and hernia repair without the use of mesh.

Apr 19, 2019

26-year-old male suffering from microstomia resulting from radiotherapy about 12 years ago following cavum carcinoma classified as T3N0M0. The preliminary impressions were made with irreversible hydrocolloid impression material. Oral hygiene instructions and prosthesis insertion and removal were imparted. The patient was satisfied with the esthetics and functional ability of the dentures.

Apr 19, 2019

Case presenting with a complication of delayed presentation from a vascular injury at the time of retropubic sling arm removal which has not previously been documented in the literature. Prevention is accomplished by proper visualization of pelvic vasculature and/or eliminating tension on sling before excision.